What is the size of the product?

The length of the product is 135mm, Ø 53mm.

What is the volume of the Alteco LPS Adsorber?

The volume of the Alteco LPS Adsorber is approximately 100ml.

What material is the product made of?

The housing and endcaps are made of an acrylic-based polymer compound. The porous discs are made of polyethylene (HDPE resin).

Are there any toxic materials or components in the product?

No, this was studied in detail in the product development process and there are no toxic materials or substances in the Alteco LPS Adsorber.

What is the surface area of the product?

The Alteco LPS Adsorber uses a surface area of approximately 4m 2. When blood comes into contact with large artificial surfaces, it induces a systemic response. 1 The smaller the surface area, the less complement activation in the immune system – hence, an optimized surface area is beneficial.

What is the shelf life of the product?

The shelf life of the Alteco LPS Adsorber is 3 years.

Where can I get the tubing lines needed for the treatment?

The Alteco LPS Adsorber is intended for use with standard, commercially available bloodlines compatible with the blood purification system used.

Alteco LPS Adsorber inlet and outlet connectors are standard dialysis
connectors (ISO 8637) and are therefore compatible with various blood purification systems available on the market.

When should treatment be started?

For best treatment results, the Alteco LPS Adsorber should be used as early as possible in hemoperfusion (HP), before acute kidney injury (AKI) escalates and the need for continuous renal replacement therapy (CRRT) arises. Start treatment when the patient shows signs of imminent clinical deterioration, meaning:

  • Urine production is decreasing (acute kidney failure approaching)
  • Mean arterial pressure (MAP) ~ 65 mmHg
  • >2 hours of vasopressor support and patient still unstable
What catheter should be used for access?

A double lumen dialysis catheter of size 12-14F is required to obtain sufficient blood flow rate of 150 ± 50 ml/min. A femoral Seldinger catheter can also be used.

Why does the product need to be rinsed?

Rinsing of the Alteco LPS Adsorber is important to wash out the glycerin used as a stabilizer in the adsorber.

How long is the treatment time?

Run the treatment procedure for 2-6 hours. Discontinue treatment when hemodynamic stabilization has been achieved.

How many treatments are needed?

The product is safe for multiple treatments. The physician in charge can determine the need for repeated treatment(s), based on the patient’s condition and hemodynamic response.

What is the recommended treatment mode?

HP (stand-alone) is the recommended treatment mode.

What is the recommended blood flow rate?

The recommended flow when using the Alteco LPS Adsorber is 150 ± 50ml/min (minimum 100ml/min and maximum 200ml/min).

Can the product be combined with CRRT?

The recommended treatment mode is HP, but the product can be used in CRRT as well. If placed in series with a dialysis membrane, the Alteco LPS Adsorber shall be placed before the dialysis membrane and blood flow must not exceed 200 ml/min during the treatment.

Can the product be re-sterilized and reused?

No, the Alteco LPS Adsorber is meant for single use only and cannot be resterilized.