Patients should be treated with Alteco LPS Adsorber to remove endotoxin (lipopolysaccharide, LPS) from the bloodstream, to impede spiraling chain reactions in the immune system. 1 This can turn the course of sepsis and stabilize the patient’s hemodynamic parameters in 2 hours. 2

What treatment results to expect

For septic patients, usually one treatment is enough. Post treatment, patients demonstrate:

• Reduction in endotoxin, procalcitonin (PCT) and lactate levels 3
• Improved tissue perfusion 4
• Positive effects on leukocytosis levels 5
• Positive effects on body temperature 6
• Increase in lung oxygenating function 7
• Reduction or elimination of vasopressor support dependence 8
• Stability and improvement in mean arterial pressure (MAP), heart rate (HR) and oxygen saturation 9
• Improved SOFA score 10

Endotoxin removal

Inside the Alteco LPS Adsorber, a tailor-made synthetic peptide binds to Lipid A; the toxic part of endotoxin. By adsorbing harmful levels of endotoxin from the patient’s bloodstream during extracorporeal treatment in the ICU, the Alteco LPS Adsorber breaks the chain of immune system over-reactions that can spiral into septic shock. This can turn the course of sepsis and stabilize the patient’s hemodynamic parameters in 2 hours. 2

Take endotoxin out of the picture

View our product animation to learn more about endotoxin removal and the Alteco LPS Adsorber.

Turn the course of sepsis

High levels of endotoxin activity are associated with organ failure and death. 3 Therefore, starting treatment early is important. Use the Alteco LPS Adsorber to counteract the critical and life-threatening part of the sepsis process. Remove endotoxin from the bloodstream to regain control over the systemic failure and stabilize the patient in the acute situation.